PEG-coated nanoparticles detachable in acidic microenvironments for the tumor-directed delivery of chemo- and gene therapies for head and neck cancer
Yu‐Li Lo, Chih-Hsien Chang, Chen-Shen Wang, Muh‐Hwa Yang, Anya Maan-Yuh Lin, Ci-Jheng Hong, Wei-Hsuan Tseng
Abstract
Chemotherapy and gene therapy co-treatment involving pH-sensitive and targeting peptide-modified nanoparticles may be an innovative strategy for HNC treatment.
Topics & Concepts
Head and neck cancerPEG ratioGene deliveryCancer researchCancerTumor microenvironmentNanoparticleHead and neckChemistryGeneMedicineGenetic enhancementNanotechnologyMaterials scienceBiochemistryTumor cellsInternal medicineSurgeryEconomicsFinanceRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryDrug Transport and Resistance Mechanisms