Piperidine nucleus in the field of drug discovery
Mennatallah Mahmoud Abdelshaheed, Iten M. Fawzy, Hussein I. El‐Subbagh, Khairia M. Youssef
Abstract
Abstract Background Piperidine is an essential heterocyclic system and a pivotal cornerstone in the production of drugs. Piperidine byproducts showed several important pharmacophoric features and are being utilized in different therapeutic applications. Main text Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents. Conclusions This review article sheds a light on the most recent studies proving the importance of piperidine nucleus in the field of drug discovery.
Topics & Concepts
PiperidineAntifungalDrugChemistryPharmacologyMedicineStereochemistryDermatologyPiperaceae Chemical and Biological StudiesComputational Drug Discovery MethodsChemical Synthesis and Analysis