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Partial least squares regression and principal component analysis: similarity and differences between two popular variable reduction approaches

Chenyu Liu, Xinlian Zhang, Tanya T. Nguyen, Jinyuan Liu, Tsung‐Chin Wu, Ellen Lee, Xin Tu

2022General Psychiatry80 citationsDOIOpen Access PDF

Abstract

In many statistical applications, composite variables are constructed to reduce the number of variables and improve the performances of statistical analyses of these variables, especially when some of the variables are highly correlated. Principal component analysis (PCA) and factor analysis (FA) are generally used for such purposes. If the variables are used as explanatory or independent variables in linear regression analysis, partial least squares (PLS) regression is a better alternative. Unlike PCA and FA, PLS creates composite variables by also taking into account the response, or dependent variable, so that they have higher correlations with the response than composites from their PCA and FA counterparts. In this report, we provide an introduction to this useful approach and illustrate it with data from a real study.

Topics & Concepts

Partial least squares regressionPrincipal component analysisStatisticsRegression analysisVariablesLinear regressionPrincipal component regressionMathematicsRegressionRegression diagnosticVariable (mathematics)Design matrixEconometricsPolynomial regressionMathematical analysisNutritional Studies and DietSensory Analysis and Statistical MethodsSpectroscopy and Chemometric Analyses