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Inhibiting specificity protein 1 attenuated sevoflurane-induced mitochondrial stress and promoted autophagy in hippocampal neurons through PI3K/Akt/mTOR and α7-nAChR signaling

Guoying Lv, Weiwei Wang, Manyi Sun, Fengjuan Wang, Yonglei Ma, Chuangang Li

2022Neuroscience Letters16 citationsDOI

Topics & Concepts

SevofluranePI3K/AKT/mTOR pathwayAutophagyProtein kinase BHippocampal formationOxidative stressCell biologyHippocampusChemistryPharmacologyBiologySignal transductionNeuroscienceApoptosisBiochemistryAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive DisordersCardiac Ischemia and Reperfusion
Inhibiting specificity protein 1 attenuated sevoflurane-induced mitochondrial stress and promoted autophagy in hippocampal neurons through PI3K/Akt/mTOR and α7-nAChR signaling | Litcius