Size-Tunable Metal–Organic Framework-Coated Magnetic Nanoparticles for Enzyme Encapsulation and Large-Substrate Biocatalysis
Qiaobin Li, Yanxiong Pan, Hui Li, Lina Alhalhooly, Yue Li, Bingcan Chen, Yongki Choi, Zhongyu Yang
Abstract
/BDC concentrations. While the microscale composites showed significantly enhanced reusability against a non-structured large substrate, the nanoscale composites displayed enhanced catalytic efficiency against a rigid, crystalline-like large substrate, starch, likely due to the improved diffusivity of the nanoscale composites. To our best knowledge, this is the first report on aqueous-phase one-pot synthesis of size-tunable enzyme@MOF/MNP composites for large-substrate biocatalysis. Our platform can be applied to immobilize other large-substrate enzymes with enhanced reusability and tunable sizes.
Topics & Concepts
Materials scienceBiocatalysisMetal-organic frameworkImmobilized enzymeNanoparticleChemical engineeringCatalysisSubstrate (aquarium)Aqueous solutionMagnetic nanoparticlesAqueous two-phase systemComposite numberNanotechnologyComposite materialEnzymeOrganic chemistryChemistryAdsorptionReaction mechanismOceanographyGeologyEngineeringEnzyme Catalysis and ImmobilizationElectrochemical sensors and biosensorsAdvanced Nanomaterials in Catalysis