N-Heterocyclic carbene-palladium-PEPPSI complexes and their catalytic activity in the direct C–H bond activation of heteroarene derivatives with aryl bromides: synthesis, and antimicrobial and antioxidant activities
Naceur Hamdi, Ichraf Slimani, Lamjed Mansour, Faisal Alresheedi, Nevın Gürbüz, İsmaıl Özdemır
Abstract
The Pd–NHC–PEPPSI complexes were used as catalysts in the direct C 5 -arylation of 2-acetyl furan, 2-acetylthiophene, and 2 n -propylthiazole with different aryl bromides and were evaluated for their potential antibacterial and antioxidant properties.
Topics & Concepts
ChemistryArylPalladiumAntimicrobialCarbeneFuranCatalysisAntioxidantOrganic chemistryMedicinal chemistryCombinatorial chemistryAlkylN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods