Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications
Dongdong Xu, Yang Li, Shouchun Yin, Feihe Huang
Abstract
circulation stability of SCCs, alongside minimizing their side effects during treatment. Addressing these challenges is crucial for advancing the fundamental research of SCCs and their subsequent clinical translation. In this review, drawing on extensive contemporary research, we offer a thorough and systematic analysis of the strategies employed by SCCs to surmount these prevalent yet pivotal obstacles. Additionally, we explore further potential challenges and prospects for the broader application of SCCs in the biomedical field.
Topics & Concepts
MetallacycleSupramolecular chemistryKey (lock)NanotechnologySolubilityCoordination complexChemistryCombinatorial chemistryComputer scienceMetalMaterials sciencePhysicsMoleculeOrganic chemistryX-ray crystallographyDiffractionComputer securityOpticsNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and Applications