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Dual Checkpoint Inhibition in Melanoma With ≥1% PD-L1—Time to Reassess the Evidence

Marco Donia, Vinay Prasad

2024JAMA Oncology12 citationsDOIOpen Access PDF

Abstract

This Viewpoint discusses use of anti–PD-1 monotherapy as the primary treatment option for patients with treatment-naive metastatic melanoma staining positive for PD-L1 over dual checkpoint inhibition therapy.

Topics & Concepts

MedicineMelanomaOncologyPD-L1Metastatic melanomaInternal medicineDual (grammatical number)Cancer researchImmunotherapyCancerArtLiteratureCancer Immunotherapy and BiomarkersCAR-T cell therapy researchMelanoma and MAPK Pathways
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