Electrochemically Enable <i>N</i>-Sulfenylation/Phosphinylation of Sulfoximines via Oxidative Dehydrocoupling Reaction
Wenbao Zhang, Dongsheng Jin, Yongkang Hu, Kun Yin, Q. Zou, Liang Tang, Peng Qian
Abstract
An electrochemical oxidative cross-coupling strategy for the synthesis of N -sulfenylsulfoximines from sulfoximines and thiols was accomplished, giving diverse N -sulfenylsulfoximines in moderate to good yields. Moreover, this strategy can be extended to construct the N–P bond of N -phosphinylated sulfoximines. With electrons as reagents, the oxidative dehydrogenation cross-coupling reaction proceeds smoothly in the absence of traditional redox reagents.
Topics & Concepts
ChemistryDehydrogenationReagentOxidative phosphorylationRedoxOxidative coupling of methaneCombinatorial chemistryElectrochemistryCoupling reactionCoupling (piping)Organic chemistryCatalysisElectrodeBiochemistryMechanical engineeringPhysical chemistryEngineeringSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods