Biocompatible solvent selection based on thermodynamic and computational solubility models, in-silico GastroPlus prediction, and cellular studies of ketoconazole for subcutaneous delivery
Afzal Hussain, Sultan Alshehri, Mohhammad Ramzan, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Manal A. Alossaimi
Topics & Concepts
SolubilityChemistryAqueous solutionSolventCandida tropicalisPolyethylene glycolNuclear chemistryOrganic chemistryBiochemistryYeastDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesPharmacological Effects of Natural Compounds