Boosting immunotherapy of triple negative breast cancer through the synergy of mild PTT and Fe-loaded organosilica nanoparticles
Ben Yang, Hui Fu, Ronghua Kong, Gang Zheng, Xihong Wang, Yang Dong, Zhenlin Yang
Abstract
mediated Fenton reaction in concert with mild PTT. These effects resulted in the elimination of TNBC tumors without obvious side effects. Therefore, such a synergistic modality of IMOFH + mild PTT is promising for TNBC therapy.
Topics & Concepts
Boosting (machine learning)ImmunotherapyMaterials scienceBreast cancerCancer immunotherapyTriple-negative breast cancerNanoparticleTriple negativeCancer researchOncologyCancerMedicinePharmacologyInternal medicineNanotechnologyMachine learningComputer scienceNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryAdvanced Nanomaterials in Catalysis