Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export
Saeed Daneshmandi, Yan Qi, Jee Eun Choi, Eriko Katsuta, Cameron R. MacDonald, Mounika Goruganthu, Nathan Roberts, Elizabeth A. Repasky, Prashant Kumar Singh, Kristopher Attwood, Jianmin Wang, Yosef Landesman, Philip L. McCarthy, Hemn Mohammadpour
Topics & Concepts
ImmunosuppressionCancer researchDownregulation and upregulationMyeloid-derived Suppressor CellSuppressorBlockadeMAPK/ERK pathwayImmune systemSTAT3ReprogrammingMyeloidBiologyCancerImmunologySignal transductionCell biologyCellReceptorGeneGeneticsBiochemistryImmune cells in cancerImmune Response and InflammationInflammation biomarkers and pathways