Minisci reaction of heteroarenes and unactivated C(sp<sup>3</sup>)–H alkanes <i>via</i> a photogenerated chlorine radical
Zi-Tong Pan, Li-Miao Shen, Fentahun Wondu Dagnaw, Jian‐Ji Zhong, Jing‐Xin Jian, Qing‐Xiao Tong
Abstract
as a photocatalyst. The photogenerated chlorine radical contributed to the HAT of C-H and subsequently initiated this reaction. Surprisingly, salt water and even seawater can act as a chlorine radical source, which provided an enlightening idea for future organic synthesis methods.
Topics & Concepts
ChemistryChlorineChlorine atomPhotochemistryRadicalMedicinal chemistryReaction conditionsOrganic chemistryCatalysisRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry