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The TLR4/NF-κB/NLRP3 and Nrf2/HO-1 pathways mediate the neuroprotective effects of alkaloids extracted from Uncaria rhynchophylla in Parkinson's disease

Chunxia Zhang, Jiayu Zhou, Lingxin Zhuo, Wenxin Zhang, Lingrui Lv, Lingmeng Zhu, Jia‐Yi Zhang, Feng Feng, Wenyuan Liu, Lingfei Han, Wenting Liao

2024Journal of Ethnopharmacology13 citationsDOI

Topics & Concepts

NeuroprotectionNeuroinflammationParkinson's diseasePharmacologyTLR4Traditional medicineMedicineDiseaseInflammationImmunologyInternal medicineAlkaloids: synthesis and pharmacologyMagnolia and Illicium researchParkinson's Disease Mechanisms and Treatments
The TLR4/NF-κB/NLRP3 and Nrf2/HO-1 pathways mediate the neuroprotective effects of alkaloids extracted from Uncaria rhynchophylla in Parkinson's disease | Litcius