Litcius/Paper detail

Synthesis, computational and biological studies of alkyltin(IV) N-methyl-N-hydroxyethyl dithiocarbamate complexes

Jerry O. Adeyemi, Gbemisola Morounke Saibu, Lukman O. Olasunkanmi, Adewale Oluwaseun Fadaka, Mervin Meyer, Nicole Remaliah Samantha Sibuyi, Damian C. Onwudiwe, Adebola O. Oyedeji

2021Heliyon22 citationsDOIOpen Access PDF

Abstract

-hydroxyethyl dithiocarbamate in the selected cell lines, which included KMST-6, Caco-2 and A549 cell lines. The anti-inflammatory activities revealed that the two complexes have useful activities better than diclofenac used as control drug.

Topics & Concepts

DithiocarbamateChemistryDPPHCytotoxicityAntioxidantOctahedral molecular geometryProton NMRNuclear chemistryMedicinal chemistryStereochemistryOrganic chemistryIn vitroBiochemistryMoleculeOrganometallic Compounds Synthesis and CharacterizationThermal and Kinetic AnalysisCrystal structures of chemical compounds