Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of <i>Leishmania infantum</i>
Ana Perea-Martínez, Raquel García‐Hernández, José Ignacio Manzano, Francisco Gamarro
Abstract
FC ≤ -1) genes. Based on the results obtained from the analysis of RNA-seq, volcano plot, and GO enrichment analysis, we identified the most significant transcripts of relevance for their possible contribution to the TF observed in patients with leishmaniasis.
Topics & Concepts
Leishmania infantumBiologyTranscriptomeLeishmaniasisLeishmaniaGenePhenotypeImmunologyVisceral leishmaniasisDownregulation and upregulationGene expressionVirologyParasite hostingGeneticsWorld Wide WebComputer scienceResearch on Leishmaniasis StudiesTrypanosoma species research and implications