Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation
Laila A. Damiati, Monica P. Tsimbouri, Virginia Llopis-Hernández, Vineetha Jayawarna, Mark Ginty, Peter Childs, Yinbo Xiao, Karl Burgess, Julia Wells, Mark Robert Sprott, R.M. Dominic Meek, Peifeng Li, Richard O. C. Oreffo, Angela H. Nobbs, Gordon Ramage, Bo Su, Manuel Salmerón‐Sánchez, Matthew J. Dalby
Topics & Concepts
NanotopographyBiofilmMesenchymal stem cellMaterials scienceAdhesionFibronectinBiomaterialQuorum sensingCell adhesionCell biologyBone morphogenetic protein 2Regenerative medicineNanotechnologyStem cellChemistryBiologyExtracellular matrixBacteriaBiochemistryIn vitroComposite materialGeneticsOrthopedic Infections and TreatmentsBacterial biofilms and quorum sensingCellular Mechanics and Interactions