Litcius/Paper detail

Combining Inorganic Chemistry and Biology: The Underestimated Potential of Metal Complexes in Medicine

Johannes Karges

2020ChemBioChem45 citationsDOI

Abstract

The vast majority of investigated compounds in modern medicine are based on organic molecules. Within the last decades, the field of medicinial chemistry is shifting towards the application of metal complexes. These compounds offer different mechanisms of action in comparison to organic molecules due to their unique properties, making them novel drug candidates. Herein, the successful combination of metal containing compounds and medicine is highlighted by their application for photodynamic therapy.

Topics & Concepts

ChemistryNanotechnologyCombinatorial chemistryOrganic moleculesMetalMoleculeChemical biologyOrganic chemistryMaterials scienceBiochemistryMetal complexes synthesis and propertiesNanocluster Synthesis and ApplicationsNanoplatforms for cancer theranostics