Litcius/Paper detail

Hypoalbuminemia in patients following their recovery from severe coronavirus disease 2019

Kameran M. Ali, Ayad M. Ali, Hassan Mohammad Tawfeeq, Grazziela P. Figueredo, Hassan M. Rostam

2021Journal of Medical Virology20 citationsDOIOpen Access PDF

Abstract

Abstract Coronavirus disease 2019 (COVID‐19) is caused by a contagious virus that has spread to more than 200 countries, territories, and regions. Thousands of studies to date have examined all aspects of this disease, yet little is known about the postrecovery status of patients, especially in the long term. Here, we examined erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP), and serum albumin biomarkers in patients with a history of severe and mild‐to‐moderate COVID‐19 following their recovery. In patients with severe COVID‐19 serum albumin had a strong negative correlation with both ESR and CRP levels ( R 2 = − 0.861 and R 2 = − 0.711), respectively. Also, there was a positive correlation between ESR and CRP level ( R 2 = 0.85) in the same group. However, there was no correlation between these biomarkers among mild‐to‐moderate COVID‐19 patients. In addition, no correlation was recorded between the severe and mild‐to‐moderate COVID‐19 groups. This finding highlights the sustained elevation of ESR and CRP level and reduced serum albumin level that may persist postrecovery in patients with a history of severe COVID‐19.

Topics & Concepts

HypoalbuminemiaAlbuminMedicineErythrocyte sedimentation rateCoronavirus disease 2019 (COVID-19)Internal medicineGastroenterologySerum albuminCoronavirusDiseaseC-reactive proteinSeverity of illnessInfectious disease (medical specialty)InflammationCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Muscle and Compartmental Disorders