The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner
David Hamelin, Dominique Fournelle, Jean‐Christophe Grenier, Jana Schockaert, Kevin A. Kovalchik, Peter Kubiniok, Fatima Mostefai, Jérôme D. Duquette, Frederic Saab, Isabelle Sirois, Martin A. Smith, Sofie Pattijn, Hugo Soudeyns, Hélène Decaluwe, Julie Hussin, Étienne Caron
Topics & Concepts
BiologyImmunosurveillancePopulationPandemicGeneticsHuman leukocyte antigenImmunogenicityGenomeEpitopeHaplotypeVirologyAlleleCellCoronavirus disease 2019 (COVID-19)Immune systemGeneMedicineAntigenDiseaseInfectious disease (medical specialty)Environmental healthPathologySARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesImmunotherapy and Immune Responses