Utilization of methanol for condensation interrupted chemoselective transfer hydrogenation of CC, CO, and CN bonds under low catalyst loading
Anirban Sau, Divya Mahapatra, Sadhan Dey, Dibyajyoti Panja, Saghnik Saha, Sabuj Kundu
Abstract
Selective transfer hydrogenation (TH) of unsaturated molecules using methanol is challenging as the in situ generated formaldehyde is prone to react with the active methylene ( C -methylation) or amine ( N -methylation) core of the desired product.
Topics & Concepts
ChemistryFormaldehydeMethanolCatalysisMethyleneAmine gas treatingTransfer hydrogenationMethylationCondensationMoleculeOrganic chemistryMedicinal chemistryPhotochemistryDNABiochemistryPhysicsThermodynamicsRutheniumAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisCatalysis for Biomass Conversion