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A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning

Ariel Erijman, Łukasz Kozłowski, Salma Sohrabi-Jahromi, James Fishburn, Linda Warfield, Jacob Schreiber, William Stafford Noble, Johannes Söding, Steven Hahn

2020Molecular Cell139 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTranscription factorTranscription (linguistics)Activator (genetics)Computational biologyAmino acidGeneticsBiochemistryGeneLinguisticsPhilosophyGenomics and Chromatin DynamicsRNA and protein synthesis mechanismsRNA Research and Splicing