A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects
Feng Long, Hongbiao Shi, Pengyu Li, Shaoqiang Guo, Yuer Ma, Shijun Wei, Yan Li, Fei Gao, Shang Gao, Meitian Wang, Ruonan Duan, Xiaojing Wang, Kun Yang, Wenjie Sun, Xi Li, Jiangxia Li, Qiji Liu
Topics & Concepts
Cell biologyEndochondral ossificationBone morphogenetic proteinIntramembranous ossificationMutantBiologyOssificationAnatomyCartilageGeneticsGeneTGF-β signaling in diseasesHedgehog Signaling Pathway StudiesCancer-related gene regulation