Indole‐ <i>N</i> ‐Carboxylic Acids and Indole‐ <i>N</i> ‐Carboxamides in Organic Synthesis
Linwei Zeng, Yuxin Lin, Sunliang Cui
Abstract
Indoles are ubiquitous structures that are found in natural products and biologically active molecules. The synthesis of indoles and indole-involved synthetic methodologies in organic chemistry have been receiving considerable attention. Indole-N-carboxylic acids and derived indole-N-carboxamides are intriguing compounds, which have been widely used in organic synthesis, especially in multicomponent reactions and C-H functionalization of indoles. This Minireview summarizes the advances of reactions involving indole-N-carboxylic acids and indole-N-carboxamides in organic chemistry, and discusses the synthetic potential and perspective of this field.
Topics & Concepts
Indole testChemistryOrganic synthesisOrganic chemistryCombinatorial chemistryMoleculeCatalysisCatalytic C–H Functionalization MethodsSynthesis of Indole DerivativesSynthesis and Catalytic Reactions