Control of RNA with quinone methide reversible acylating reagents
Hyun Shin Park, Biswarup Jash, Lu Xiao, Yong Woong Jun, Eric T. Kool
Abstract
Reversible quinone methide acylating reagents are designed for the rapid control of RNAs ( e.g. mRNA) in vitro and in cells.
Topics & Concepts
AcylationChemistryAzideReagentCombinatorial chemistryRNAOrganic chemistryBiochemistryCatalysisGeneRNA Interference and Gene DeliveryRNA modifications and cancerRNA and protein synthesis mechanisms