Biomimetic polypyrrole/hyaluronic acid electrodes integrated with hyaluronidase inhibitors offer persistent electroactivity and resistance to cell binding
Jongdarm Yi, Sanghun Lee, Jae Young Lee
Abstract
), without cytotoxicity. These excellent properties allowed for maintenance of the electrical sensitivity of PPy/HA during cell culture with HAase. Altogether, biomimetic PPy/HA, which is resistant to degradation by HAase, may serve as an effective platform for the development of reliable and biocompatible bioelectrodes.
Topics & Concepts
PolypyrroleMaterials scienceHyaluronic acidHyaluronidaseBiocompatibilityConductive polymerAdhesiveElectrodeBiofoulingPolymerPolymer chemistryChemical engineeringChemistryMembraneNanotechnologyPolymerizationOrganic chemistryComposite materialBiochemistryEnzymeEngineeringLayer (electronics)Physical chemistryMetallurgyGeneticsBiologyConducting polymers and applicationsAdvanced Sensor and Energy Harvesting MaterialsNeuroscience and Neural Engineering