3ʹ,4ʹ-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction
Hwi‐Ho Lee, Ji‐Sun Shin, Kyung‐Sook Chung, Jae‐Min Kim, Seang-Hwan Jung, Hyung‐Seok Yoo, Ahmed H.E. Hassan, Jong Kil Lee, Kyung‐Soo Inn, Sangmin Lee, Nam‐Jung Kim, Kyung‐Tae Lee
Topics & Concepts
Proinflammatory cytokineTLR4LipopolysaccharideChemistryElectrophoretic mobility shift assayActivator (genetics)STAT proteinSTAT1In vivoIn vitroSignal transductionMolecular biologyNitric oxideNF-κBTranscription factorSTAT3PharmacologyCell biologyInflammationBiologyReceptorBiochemistryImmunologyGeneOrganic chemistryBiotechnologyImmune Response and InflammationBioactive natural compoundsPhytoestrogen effects and research