LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
Green Ahn, Steven M. Banik, Caitlyn L. Miller, Nicholas M. Riley, Jennifer R. Cochran, Carolyn R. Bertozzi
Topics & Concepts
Asialoglycoprotein receptorLysosomeCell biologyBiologyReceptorProtein degradationMannose 6-phosphate receptorInsulin-like growth factor 2 receptorBiochemistryCell surface receptorChemistryGrowth factorIn vitroInsulin-like growth factor 1 receptorEnzymeHepatocyteProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments