Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects
Paul Bruinenberg, Jerry Nedelman, Tian J. Yang, Fran Pappas, Dan Everitt
Abstract
The primary objective of the study was to evaluate the safety and tolerability of single oral doses of sutezolid tablets administered under fasting conditions in healthy adult subjects. The secondary objective was to determine the pharmacokinetics (PK) of sutezolid and two metabolites, PNU-101603 and PNU-101244.
Topics & Concepts
TolerabilityPharmacokineticsCmaxMedicinePlasma concentrationArea under the curvePharmacologyAdverse effectHelicobacter pylori-related gastroenterology studiesPharmacogenetics and Drug MetabolismPharmaceutical Practices and Patient Outcomes