FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1
Sungyun Cho, Yujin Chun, Long He, Cuauhtemoc B. Ramirez, Kripa S. Ganesh, Kyungjo Jeong, Junho Song, Jin‐Gyu Cheong, Zhongchi Li, Jungmin Choi, Joo‐Hwan Kim, Nikos Koundouros, Fangyuan Ding, Noah Dephoure, Cholsoon Jang, John Blenis, Gina Lee
Topics & Concepts
BiologyLipogenesisSterol regulatory element-binding proteinmTORC1RNA splicingCell biologyTranscription (linguistics)Transcription factorDownstream (manufacturing)EnzymeAlternative splicingGeneGeneticsBiochemistryExonSignal transductionPI3K/AKT/mTOR pathwayRNAEconomicsPhilosophyLinguisticsOperations managementCancer, Lipids, and MetabolismLipid metabolism and biosynthesisCholesterol and Lipid Metabolism