Cuproptosis-related genes score and its hub gene GCSH: A novel predictor for cholangiocarcinomas prognosis based on RNA seq and experimental analyses
Rui He, Yihu Li, Pengcheng Jiao, Yingbin Huang, Shuyi Dong, Liqiu Mo, Xingyuan Jiao
Abstract
The CRG scoring system accurately predicts prognosis and opens up new possibilities for cuproptosis-related therapy for CCA. The cuproptosis key gene GCSH has been preliminarily confirmed as a reliable therapeutic target or prognostic marker for CCA patients.
Topics & Concepts
GeneTumor microenvironmentCarcinogenesisGene expressionCancer researchBiologyComputational biologyMedicineImmune systemBioinformaticsOncologyImmunologyGeneticsCholangiocarcinoma and Gallbladder Cancer StudiesCancer-related molecular mechanisms researchMicroRNA in disease regulation