Intramolecular Aromatic C–H Acyloxylation Enabled by Iron Photocatalysis
Siqi Xia, Kunjun Hu, Chuanhu Lei, Jian Jin
Abstract
A mild and efficient protocol for the intramolecular aromatic C-H oxygenation of 2-biphenylcarboxylic acids has been achieved via iron photocatalysis. The 2-biphenylcarboxylic acids with a diverse array of substituents at both phenyl rings could furnish the oxygenation products in good to excellent yields. We speculate that the aryl carboxylate-iron(III) complexes should generate the aroyloxy radicals and iron(II) upon visible light irradiation.
Topics & Concepts
ChemistryIntramolecular forcePhotocatalysisEnvironmental chemistryOrganic chemistryCatalysisRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods