SARS-CoV-2 Aerosol Exhaled by Experimentally Infected Cynomolgus Monkeys
Chunmao Zhang, Zhendong Guo, Zongzheng Zhao, Tiecheng Wang, Liang Li, Faming Miao, Cheng Zhang, Yuanguo Li, Yuwei Gao
Abstract
We analyzed size of severe acute respiratory coronavirus 2 (SARS-CoV-2) aerosol particles shed by experimentally infected cynomolgus monkeys. Most exhaled particles were small, and virus was mainly released early during infection. By postinfection day 6, no virus was detected in breath, but air in the isolator contained large quantities of aerosolized virus.
Topics & Concepts
AerosolizationAerosolVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusCoronavirusCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakRespiratory systemBiologyMicrobiologyMedicineChemistryPathologyInhalationInfectious disease (medical specialty)AnatomyDiseaseOrganic chemistryOutbreakInfection Control and VentilationSARS-CoV-2 and COVID-19 ResearchCOVID-19 epidemiological studies