In Vivo Performance of Microstructured Bacterial Cellulose-Silk Sericin Wound Dressing: Effects on Fibrosis and Scar Formation
B Boni, Lallepak Lamboni, Laboratoire de Biologie Moléculaire et Virologie, Institut National d’Hygiène-Togo, 26 Rue Nangbéto, Quartier Administratif- PO. Box 1396, Lomé-Togo, Lin Mao, Bianza Moïse Bakadia, Zhijun Shi, Guang Yang
Abstract
Improved healing rates are obtained upon the application of the composite dressings as compared to pure BC. mBC-SS2 prevents the excessive wound contraction which leads to hypertrophied neo-tissue formation when rBC-SS2 is used. The collagen fibers are aligned along the width of microgroove of mBC and its composites while anarchic deposited in the presence of rBC and its composites. Relatively to rBC-SS2, mBC-SS2 constitutes an improved dressing with abilities of inducing rapid wound healing and reducing the risk of excessive fibrosis and scar formation.