The progress of small-molecules and degraders against BCR-ABL for the treatment of CML
Youlu Pan, Shenxin Zeng, Rongrong Hao, Meihao Liang, Zhengrong Shen, Wenhai Huang
Topics & Concepts
ImatinibMyeloid leukemiaTyrosine kinaseCancer researchPonatinibDrug resistanceImatinib mesylateChemistryDrug discoveryABLDasatinibPharmacologyBiologySignal transductionGeneticsBiochemistryProtein Degradation and InhibitorsChronic Myeloid Leukemia TreatmentsMultiple Myeloma Research and Treatments