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Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity

Longchao Liu, Jiahui Chen, Hongyi Zhang, Jianfeng Ye, Casey Moore, Changzheng Lu, Yan Fang, Yang‐Xin Fu, Bo Li

2022Nature Cancer74 citationsDOIOpen Access PDF

Topics & Concepts

T cellImmune checkpointCytotoxic T cellImmune systemImmunologyCancer researchCD8PopulationImmunotherapyBiologyMedicineIn vitroEnvironmental healthBiochemistryCAR-T cell therapy researchImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers
Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity | Litcius