SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3
Wenwen Zhang, Zhenling Ma, Yaru Wu, Xixi Shi, Yanyan Zhang, Min Zhang, Menghao Zhang, Lei Wang, Wei Liu
Topics & Concepts
IRF3Sendai virusVirologyProteaseInnate immune systemBiologyViral replicationInterferonImmune systemCoronavirusVirusImmunologyEnzymeCoronavirus disease 2019 (COVID-19)MedicineBiochemistryDiseaseInfectious disease (medical specialty)PathologySARS-CoV-2 and COVID-19 Researchinterferon and immune responsesAnimal Virus Infections Studies