Chromothripsis drives the evolution of gene amplification in cancer
Ofer Shoshani, Simon Brunner, Rona Yaeger, Peter Ly, Yael Nechemia‐Arbely, Dong Hyun Kim, Rongxin Fang, Guillaume A. Castillon, Miao Yu, Julia S. Z. Li, Ying Sun, Mark H. Ellisman, Bing Ren, Peter J. Campbell, Don W. Cleveland
Topics & Concepts
ChromothripsisBiologyExtrachromosomal DNAGene duplicationGeneticsGenome instabilityGeneChromoplexyDNACancerMolecular biologyGenomeCancer researchDNA damageProstatePCA3Cancer Genomics and DiagnosticsCRISPR and Genetic EngineeringDNA Repair Mechanisms