A <i>“</i>CPApoptosis<i>”</i> nano-actuator switches immune-off solid tumors to immune-on for fueling T-cell- based immunotherapy
Ying Luo, Yi Wang, Bo Liu, Yun Liu, Wenli Zhang, Sijin Chen, Xiyue Rong, Lian Xu, Qianying Du, Jia Liu, Jie Xu, Haitao Ran, Zhigang Wang, Dajing Guo
Abstract
The CPApoptosis nano-actuator represents a promising approach to enhance current cancer therapies, inducing both tumor cell death and a robust immune response, with the potential for long-lasting protective effects.
Topics & Concepts
Immune systemImmunotherapyMedicineCancer researchImmunologyNanoplatforms for cancer theranosticsCAR-T cell therapy researchNanoparticle-Based Drug Delivery