Litcius/Paper detail

Design, synthesis and in vitro cytotoxic evaluation of β-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors

Jay Prakash Soni, Priyanka Devi, Sowjanya Chemitikanti, Anamika Sharma, Chintha Venkata Dinesh Swamy, Regur Phanindranath, Manda Sathish, Narayana Nagesh, Chandraiah Godugu, Nagula Shankaraiah

2023Journal of Molecular Structure12 citationsDOI

Topics & Concepts

ChemistryCytotoxicityQuinolineMCF-7ApoptosisIn silicoIC50In vitroStereochemistryCell cultureDNACancer cellBiochemistryCancerGeneticsGeneBiologyHuman breastOrganic chemistrySynthesis and bioactivity of alkaloidsCancer therapeutics and mechanismsHIV/AIDS drug development and treatment