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Biological activity-based modeling identifies antiviral leads against SARS-CoV-2

Ruili Huang, Miao Xu, Hu Zhu, Catherine Z. Chen, Wei Zhu, Emily M. Lee, Shihua He, Li Zhang, Jinghua Zhao, Khalida Shamim, Danielle Bougie, Wenwei Huang, Menghang Xia, Mathew D. Hall, Donald C. Lo, Anton Simeonov, Christopher P. Austin, Xiangguo Qiu, Hengli Tang, Wei Zheng

2021Nature Biotechnology52 citationsDOIOpen Access PDF

Topics & Concepts

Drug discoveryComputational biologyBiological activityDrugHigh-throughput screeningSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Antiviral drugBiologyChemistryCoronavirus disease 2019 (COVID-19)PharmacologyIn vitroBioinformaticsBiochemistryMedicineInfectious disease (medical specialty)DiseasePathologyMosquito-borne diseases and controlComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2 | Litcius