Cyclotron-produced 68Ga from enriched 68Zn foils
Jonathan Siikanen, Emma Jussing, Stefan Milton, Carsten Steiger, Johan Ulin, Cathrine Jonsson, Erik Samén, Thuy Tran
Abstract
The growing need and limited availability of generator produced 68Ga (T1/2 = 68 min) for PET has provided the impetus for alternative, high output, 68Ga production routes such as charge particle activation of enriched 68Zn using PET cyclotrons. The work presents a rapid production method for clinically useful 68Ga for radiolabeling. The focus is also to expand the production capacity of cyclotron solid target-produced 68Ga over generator produced and liquid solutions targets by using enriched 68Zn-foils that minimizes target preparation.
Topics & Concepts
CyclotronGenerator (circuit theory)Production (economics)RadiochemistryChemistryMaterials sciencePhysicsNuclear physicsPlasmaPower (physics)Quantum mechanicsEconomicsMacroeconomicsPeptidase Inhibition and AnalysisRadiopharmaceutical Chemistry and ApplicationsCardiac Structural Anomalies and Repair