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Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) — United States, February 12–March 16, 2020

CDC COVID-19 Response Team, CDC COVID-19 Response Team, Stephanie R. Bialek, Ellen O. Boundy, Virginia B. Bowen, Nancy A. Chow, Amanda Cohn, Nicole F. Dowling, Sascha Ellington, Ryan Gierke, Aron J. Hall, Jessica R. MacNeil, Priti R. Patel, Georgina Peacock, Tamara Pilishvili, Hilda Razzaghi, Nia Reed, Matthew D. Ritchey, Erin K. Sauber‐Schatz

2020MMWR Morbidity and Mortality Weekly Report2,423 citationsDOIOpen Access PDF

Abstract

Globally, approximately 170,000 confirmed cases of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) have been reported, including an estimated 7,000 deaths in approximately 150 countries (1). On March 11, 2020, the World Health Organization declared the COVID-19 outbreak a pandemic (2). Data from China have indicated that older adults, particularly those with serious underlying health conditions, are at higher risk for severe COVID-19-associated illness and death than are younger persons (3). Although the majority of reported COVID-19 cases in China were mild (81%), approximately 80% of deaths occurred among adults aged ≥60 years; only one (0.1%) death occurred in a person aged ≤19 years (3). In this report, COVID-19 cases in the United States that occurred during February 12-March 16, 2020 and severity of disease (hospitalization, admission to intensive care unit [ICU], and death) were analyzed by age group. As of March 16, a total of 4,226 COVID-19 cases in the United States had been reported to CDC, with multiple cases reported among older adults living in long-term care facilities (4). Overall, 31% of cases, 45% of hospitalizations, 53% of ICU admissions, and 80% of deaths associated with COVID-19 were among adults aged ≥65 years with the highest percentage of severe outcomes among persons aged ≥85 years. In contrast, no ICU admissions or deaths were reported among persons aged ≤19 years. Similar to reports from other countries, this finding suggests that the risk for serious disease and death from COVID-19 is higher in older age groups.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)OutbreakPandemicIntensive care unitDiseasePediatricsYoung adultSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DemographyGerontologyInfectious disease (medical specialty)Internal medicineVirologySociologyCOVID-19 and healthcare impactsCOVID-19 Clinical Research StudiesCOVID-19 and Mental Health