Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors
Sara Rahimzadeh Oskuei, Salimeh Mirzaei, Mohammad Reza Jafari-Nik, Farzin Hadizadeh, Farhad Eisvand, Fatemeh Mosaffa, Razieh Ghodsi
Topics & Concepts
ChemistryChalconeCytotoxicityTubulinCancer cellAnnexinApoptosisA549 cellCell cycleCell cultureCell cycle checkpointCancer researchBiochemistryCancerIn vitroCell biologyBiologyMicrotubuleStereochemistryGeneticsSynthesis and biological activitySynthesis and Biological EvaluationClick Chemistry and Applications