Calcium phosphate bone cements with α-ketoglutarate polyester microspheres promote osteoporotic bone defect repair
Zhengyang Kang, Hui Yang, Xinzhi Liang, Bin Wu, Dequan Wang, Tingliang Xiong, Luhui Zhang, Denghui Xie
Abstract
signaling pathway. Notably, the addition of 10 wt% α-KG polyester microspheres resulted in the optimal osteogenic capacity for CPC/α-KG. In conclusion, the modified α-KG composites show potential as effective candidates for bone defect repair and regeneration.
Topics & Concepts
CalciumMineralization (soil science)Bone healingMaterials scienceOsteoblastMicrospherePhosphateDentistryChemistryChemical engineeringMedicineMetallurgyBiochemistrySurgeryOrganic chemistryIn vitroNitrogenEngineeringBone Tissue Engineering MaterialsGraphene and Nanomaterials ApplicationsBone Metabolism and Diseases