Developing targeted therapies for neuroblastoma by dissecting the effects of metabolic reprogramming on tumor microenvironments and progression
Wenyi Jin, Yubiao Zhang, Zhijie Zhao, Mingyong Gao
Abstract
This study provides deep insights into the molecular mechanisms underlying metabolic reprogramming-mediated malignant progression of NB. It also sheds light on developing targeted medications guided by the novel precise risk prognostication approaches, which could contribute to a significantly improved therapeutic strategy for NB.
Topics & Concepts
NeuroblastomaReprogrammingMedicineCancer researchBiologyNeuroscienceBioinformaticsGeneticsCellCell cultureNeuroblastoma Research and TreatmentsCancer, Hypoxia, and MetabolismATP Synthase and ATPases Research