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Py-2NO ligand enabled Ni(<scp>ii</scp>)-catalyzed asymmetric Michael addition reaction of indoles with β,γ-unsaturated α-keto esters

Zi‐Yue Chen, Xirui Wang, Ke‐Lan Xu, Pan Hu, You‐Ping Tian, Huijuan Wang, Ying Zhou, Xiong‐Li Liu

2024New Journal of Chemistry14 citationsDOI

Abstract

This work diversified the Py-2NO ligand library recently developed by our group and further expanded the application of chiral Py-2NO ligands in asymmetric catalysis.

Topics & Concepts

ChemistryMichael reactionCatalysisLigand (biochemistry)Medicinal chemistryOrganic chemistryReceptorBiochemistryAxial and Atropisomeric Chirality SynthesisAsymmetric Synthesis and CatalysisCatalytic C–H Functionalization Methods
Py-2NO ligand enabled Ni(<scp>ii</scp>)-catalyzed asymmetric Michael addition reaction of indoles with β,γ-unsaturated α-keto esters | Litcius