Monoclonal gammopathy of thrombotic/thrombocytopenic significance
Adam J. Kanack, Jordan K. Schaefer, Meera Sridharan, Noah P. Splinter, Mindy Kohlhagen, Bandana Singh, Silvana B. De Lorenzo, Emily Mauch, Maen Hussein, Marwan Shaikh, Shaji Kumar, Renren Wen, Demin Wang, David Murray, Anand Padmanabhan
Abstract
][5][6][7] Here, we present the case of a patient with recurrent thrombosis and thrombocytopenia, secondary to a persistent anti-PF4/polyanion monoclonal antibody due to an underlying neoplastic condition, which we refer to as monoclonal gammopathy of thrombotic/thrombocytopenic significance (MGTS).The implications of these findings for the investigation of unexplained thrombophilia are discussed.
Topics & Concepts
MedicineGeneral surgeryLibrary scienceComputer scienceHeparin-Induced Thrombocytopenia and ThrombosisMultiple Myeloma Research and TreatmentsPlatelet Disorders and Treatments