Scratching beneath the surface: catalyst evolution and reusability in the direct mechanocatalytic Sonogashira reaction
Sheeniza Shah, M. Mokhtar, Thinh Huy Tran, Kathleen Floyd, Lizette Mella, Tim Dao, Alexandria Garza, James D. Batteas, James Mack
Abstract
Mechanochemistry facilitates the in situ combination of catalyst components, including ligands and metals, while temperature control enables coupling reactions to proceed under solvent-free, aerobic conditions.
Topics & Concepts
CatalysisMechanochemistryReusabilitySonogashira couplingChemistryChemical engineeringCoupling (piping)Coupling reactionMaterials scienceCombinatorial chemistryPolymer chemistryNanotechnologyReaction conditionsHeterogeneous catalysisReaction mechanismWork (physics)NanoparticleCrystallography and molecular interactionsCatalysis and Oxidation ReactionsBacterial Infections and Vaccines