Size and density measurements of single sickle red blood cells using microfluidic magnetic levitation
Utku Goreke, Allison Bode, Sena Yaman, Umut A. Gürkan, Naside Gözde Durmus
Abstract
= 003 for RDW, linear regression). Our magnetic levitation-based assay enables rapid, accurate, density-based imaging, profiling and label-free monitoring of single RBCs. Our approach can be broadly applicable to investigate blood cell disorders and the effects of emerging pharmacological and curative therapies in patient outcomes.
Topics & Concepts
Red blood cellMicrochannelLevitationChemistryHemoglobinMaterials scienceBiophysicsNanotechnologyBiologyMagnetPhysicsBiochemistryQuantum mechanicsErythrocyte Function and PathophysiologyHemoglobinopathies and Related DisordersBlood properties and coagulation